China Diosmin Suppliers - Factory for Blood Vessel Protection and Enhanced Microcirculation Solutions

Product Introduction

• Product name: Diosmin
• Cas number: 520-27-4
• Origin: Also known as yanoside, geranitin, bucitrin, exists in the Zanthoxlum nitidum(RoxbDC) root and the fruit of Citrus modical Var.Sarcodactylis(Nool.)Swinglo, Citruslimon Brurm peel extract.
• Synthesis
• Physical properties: White or light yellow powder. Almost insoluble in water and ethanol, soluble in dimethyl sulfoxide, soluble in alkaline solution.
• Molecular formula & Molecular weight: C28H32O15 & 608.54
• Specification: EP11, USP, Russia ND, Micronized
• Ingredient content: Diosmin 92%, water 8%

Pharmacological Action

• Increase venous tension: Enhance venous wall tension, reduce venous plexus expansion, and prevent arteriovenous anastomosis dysfunction.
• Improve microcirculation: It can reduce the adhesion, migration and disintegration of inflammatory substances released by white blood cells and vascular endothelial cells, so as to protect microcirculation, maintain high permeability of capillaries and reduce microcirculation stagnation.
• Reduce edema: Increase the speed of lymphatic drainage and lymphatic contraction, accelerate the interorganizational fluid and lymphatic reflux, reduce edema.

Uses: It has a vitamin P-like effect, can reduce vascular fragility and abnormal permeability, and is also used as an auxiliary treatment for the prevention and treatment of hypertension and arteriosclerosis. It is more effective than Rutin and hesperidin in the treatment of capillary fragility.

It is an oral phlebotropic drug used in the treatment of venous disease, including chronic venous insufficiency(CVI) spider and varicose veins, leg swelling (edema), stasis dermatitis and venous ulcers. It is also used as a stand-alone or surgical adjunctive therapy in hemorrhoidal disease (HD). There are extensive clinical trials that show Diosmin improves all stages of venous disease including venous ulcers and improves quality of life.

Indications: Treatment of various symptoms related to venous and lymphatic insufficiency (such as venous edema, soft tissue swelling, heaviness of the limbs, numbness, pain, soreness and discomfort in the morning, thrombophlebitis and deep vein thrombosis syndrome, etc.); treatment of various symptoms of acute hemorrhoid attacks (such as acute attacks of internal and external hemorrhoids such as anal wetness, itching, blood in the stool, pain caused by varicose veins).