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Diosmin: China Suppliers and Factory for Blood Vessel Protection, Anti-inflammatory, and Cosmetic Solutions
Product Introduction
1. Product name: Diosmin
2. Cas number: 520-27-4
3. Origin: Also known as yanoside, geranitin, bucitrin, exists in the Zanthoxlum nitidum(RoxbDC) root and the fruit of Citrus modical Var.Sarcodactylis(Nool.)Swinglo, Citruslimon Brurm peel extract.
4. Synthesis
5. Physical properties: White or light yellow powder. Almost insoluble in water and ethanol, soluble in dimethyl sulfoxide, soluble in alkaline solution.
6. Molecular formula & Molecular weight: C28H32O15 & 608.54
Specification: EP11, USP, Russia ND, Micronized
Ingredient content: Diosmin 92%, water 8%
Pharmacological Action
1. Increase venous tension: enhance venous wall tension, reduce venous plexus expansion, and prevent arteriovenous anastomosis dysfunction.
2. Improve microcirculation: it can reduce the adhesion, migration and disintegration of inflammatory substances released by white blood cells and vascular endothelial cells, so as to protect microcirculation, maintain high permeability of capillaries and reduce microcirculation stagnation.
3. Reduce edema: increase the speed of lymphatic drainage and lymphatic contraction, accelerate the interorganizational fluid and lymphatic reflux, reduce edema.
Product Function
Uses: It has a vitamin P-like effect, can reduce vascular fragility and abnormal permeability, and is also used as an auxiliary treatment for the prevention and treatment of hypertension and arteriosclerosis. It is more effective than Rutin and hesperidin in the treatment of capillary fragility.
It is an oral phlebotropic drug used in the treatment of venous disease, including chronic venous insufficiency(CVI) spider and varicose veins, leg swelling (edema), stasis dermatitis and venous ulcers. It is also used as a stand-alone or surgical adjunctive therapy in hemorrhoidal disease (HD). There are extensive clinical trials that show Diosmin improves all stages of venous disease including venous ulcers and improves quality of life.
Indications: Treatment of various symptoms related to venous and lymphatic insufficiency (such as venous edema, soft tissue swelling, heaviness of the limbs, numbness, pain, soreness and discomfort in the morning, thrombophlebitis and deep vein thrombosis syndrome, etc.); treatment of various symptoms of acute hemorrhoid attacks (such as acute attacks of internal and external hemorrhoids such as anal wetness, itching, blood in the stool, pain caused by varicose veins).
Application Field
Diosmin in addition to its application in the medical field, it is also widely used in other areas.
Cosmetic field: In the cosmetic field, Diosmin is favored for its antioxidant and anti-inflammatory properties. It can promote the synthesis of collagen, enhance skin elasticity, and reduce wrinkle formation. At the same time, Diosmin can also improve skin microcirculation, increase skin nutrient supply, and enhance skin vitality. Diosmin is increasingly used in anti-aging cosmetics, especially in anti-wrinkle, whitening, moisturizing and other aspects.
Food additives: Diosmin can also be used as a food additive to improve the color, flavor and nutritional value of food. Due to its natural origin and biological activity, Diosmin is considered a safe and healthy food additive.
Frequently Asked Questions
What is Diosmin?
Diosmin, also known as yanoside, geranitin, or bucitrin, is a flavonoid naturally found in the Zanthoxlum nitidum root and Citrus limon peel extract. Its molecular formula is C28H32O15.
What are the physical properties of Diosmin?
It appears as a white or light yellow powder. It is almost insoluble in water and ethanol, but it is soluble in dimethyl sulfoxide and alkaline solutions.
How does Diosmin work pharmacologically?
It increases venous wall tension, improves microcirculation by reducing the adhesion and migration of inflammatory substances, and reduces edema by accelerating lymphatic drainage and fluid reflux.
What are the primary indications for taking Diosmin?
It is mainly used to treat symptoms related to venous and lymphatic insufficiency (such as venous edema, heaviness of limbs, deep vein thrombosis syndrome) and various symptoms of acute hemorrhoid attacks.
Can Diosmin be used in cosmetic products?
Yes, in the cosmetic field, Diosmin is highly valued for its antioxidant and anti-inflammatory properties. It promotes collagen synthesis, enhances skin elasticity, reduces wrinkles, and improves skin microcirculation.
Is Diosmin safe to be used as a food additive?
Yes, Diosmin can be used as a food additive to improve the color, flavor, and nutritional value of food. Due to its natural origin and biological activity, it is considered a safe and healthy additive.