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Diosmin for Vascular Protection: China Suppliers & Factory for Medical, Cosmetic, and Food Additives
Product Introduction
- Product name: Diosmin
- Cas number: 520-27-4
- Origin: Also known as yanoside, geranitin, bucitrin, exists in the Zanthoxlum nitidum(RoxbDC) root and the fruit of Citrus modical Var.Sarcodactylis(Nool.)Swinglo, Citruslimon Brurm peel extract.
- Synthesis
- Physical properties: White or light yellow powder. Almost insoluble in water and ethanol, soluble in dimethyl sulfoxide, soluble in alkaline solution.
- Molecular formula & Molecular weight: C28H32O15 & 608.54
Specification: EP11, USP, Russia ND, Micronized
Ingredient content: Diosmin 92%, water 8%
Pharmacological action
- Increase venous tension: Enhance venous wall tension, reduce venous plexus expansion, and prevent arteriovenous anastomosis dysfunction.
- Improve microcirculation: Reduce the adhesion, migration, and disintegration of inflammatory substances released by white blood cells and vascular endothelial cells to protect microcirculation, maintain high permeability of capillaries, and reduce microcirculation stagnation.
- Reduce edema: Increase the speed of lymphatic drainage and lymphatic contraction, accelerate the interorganizational fluid and lymphatic reflux, reduce edema.
Product Function
Uses: It has a vitamin P-like effect, can reduce vascular fragility and abnormal permeability, and is also used as an auxiliary treatment for the prevention and treatment of hypertension and arteriosclerosis. It is more effective than Rutin and hesperidin in the treatment of capillary fragility.
It is an oral phlebotropic drug used in the treatment of venous disease, including chronic venous insufficiency(CVI) spider and varicose veins, leg swelling (edema), stasis dermatitis and venous ulcers. It is also used as a stand-alone or surgical adjunctive therapy in hemorrhoidal disease (HD). There are extensive clinical trials that show Diosmin improves all stages of venous disease including venous ulcers and improves quality of life.
Indications: Treatment of various symptoms related to venous and lymphatic insufficiency (such as venous edema, soft tissue swelling, heaviness of the limbs, numbness, pain, soreness and discomfort in the morning, thrombophlebitis and deep vein thrombosis syndrome, etc.); treatment of various symptoms of acute hemorrhoid attacks (such as acute attacks of internal and external hemorrhoids such as anal wetness, itching, blood in the stool, pain caused by varicose veins).
Application Field
Diosmin, in addition to its application in the medical field, is also widely used in other areas.
Cosmetic Field
In the cosmetic field, Diosmin is favored for its antioxidant and anti-inflammatory properties. It can promote the synthesis of collagen, enhance skin elasticity, and reduce wrinkle formation. At the same time, Diosmin can also improve skin microcirculation, increase skin nutrient supply, and enhance skin vitality. Diosmin is increasingly used in anti-aging cosmetics, especially in anti-wrinkle, whitening, moisturizing, and other aspects.
Food Additives
Diosmin can also be used as a food additive to improve the color, flavor, and nutritional value of food. Due to its natural origin and biological activity, Diosmin is considered a safe and healthy food additive.
Frequently Asked Questions (FAQ)
What is the CAS number and origin of Diosmin?
The CAS number of Diosmin is 520-27-4. It naturally exists in the Zanthoxlum nitidum (RoxbDC) root, the fruit of Citrus modical Var. Sarcodactylis (Nool.) Swinglo, and Citrus limon Brurm peel extract.
What are the physical properties of this product?
It appears as a white or light yellow powder. It is almost insoluble in water and ethanol, but soluble in dimethyl sulfoxide and alkaline solutions.
What are the main pharmacological actions of Diosmin?
It primarily functions to increase venous tension, improve microcirculation by reducing inflammatory substance adhesion, and reduce edema by accelerating lymphatic drainage.
What medical conditions is Diosmin used to treat?
It is widely used to treat venous diseases such as chronic venous insufficiency (CVI), varicose veins, leg swelling, venous ulcers, and acute hemorrhoid attacks.
How is Diosmin applied in the cosmetic industry?
Due to its antioxidant and anti-inflammatory properties, it is used in anti-aging cosmetics to promote collagen synthesis, enhance skin elasticity, reduce wrinkles, and improve skin microcirculation.
Is Diosmin safe to be used as a food additive?
Yes, because of its natural botanical origin and beneficial biological activity, Diosmin is considered a safe and healthy food additive used to enhance food color, flavor, and nutritional value.