Protection of blood vessels - Diosmin

Diosmin's application range:

A. Medical field
1. Venous insufficiency, drugs to enhance venous tension and vascular protectors.
2. Anti-inflammatory and antioxidant.
3. Diosmin can mprove microcirculation. Reduce the permeability of capillaries and enhance their tension.
4. Promote lymphatic return and reduce edema.
5. Treat acute hemorrhoid attacks.

B. Cosmetic field
1. Diosmin can romote collagen synthesis and enhance skin elasticity.
2. Improve skin microcirculation and increase skin nutrition supply.

Food additives

Diosmin can be used as a food additive to improve the color, flavor and nutritional value of food.

product details

PRODUCT INTRODUCTION

1. Product name: Diosmin
2. Cas number: 520-27-4
3. Origin: Also known as yanoside, geranitin, bucitrin, exists in the Zanthoxlum nitidum(RoxbDC) root and the fruit of Citrus modical Var.Sarcodactylis(Nool.)Swinglo, Citruslimon Brurm peel extract.
4. Synthesis
5. Physical properties: White or light yellow powder. Almost insoluble in water and ethanol, soluble in dimethyl sulfoxide, soluble in alkaline solution.
6. Molecular formula & Molecular weight: C28H32O15&608.54

Specification: EP11,USP,Russia ND,Micronized
Ingredient content: Diosmin 92%, water 8%

Pharmacological action

1. Increase venous tension to enhance venous wall tension, reduce venous plexus expansion, and prevent arteriovenous anastomosis dysfunction.
2. Improve microcirculation: it can reduce the adhesion, migration and disintegration of inflammatory substances released by white blood cells and vascular endothelial cells, so as to protect microcirculation, maintain high permeability of capillaries and reduce microcirculation stagnation.
3. Reduce edema: increase the speed of lymphatic drainage and lymphatic contraction, accelerate the interorganizational fluid and lymphatic reflux, reduce edema.

product function

Uses: It has a vitamin P-like effect, can reduce vascular fragility and abnormal permeability, and is also used as an auxiliary treatment for the prevention and treatment of hypertension and arteriosclerosis. It is more effective than Rutin and hesperidin in the treatment of capillary fragility.

lt is an oral phlebotropic drug used in the treatment of venous disease, including chronic venous insufficiency(CVI) spider and varicose veins, leg swelling (edema), stasis dermatitis and venous ulcers. lt is also used as a stand-alone or surgical adjunctive therapy in hemorrhoidal disease (HD). There are extensive clinical trials that show Diosmin improves all stages of venous disease including venous ulcers and improves quality of life.

Indications: Treatment of various symptoms related to venous and lymphatic insufficiency (such as venous edema, soft tissue swelling, heaviness of the limbs, numbness, pain, soreness and discomfort in the morning, thrombophlebitis and deep vein thrombosis syndrome, etc.); treatment of various symptoms of acute hemorrhoid attacks (such as acute attacks of internal and external hemorrhoids such as anal wetness, itching, blood in the stool, pain caused by varicose veins).

Application field

Diosmin in addition to its application in the medical field, it is also widely used in other areas.
Cosmetic field: In the cosmetic field, Diosmin is favored for its antioxidant and anti-inflammatory properties. It can promote the synthesis of collagen, enhance skin elasticity, and reduce wrinkle formation. At the same time, Diosmin can also improve skin microcirculation, increase skin nutrient supply, and enhance skin vitality. Diosmin is increasingly used in anti-aging cosmetics, especially in anti-wrinkle, whitening, moisturizing and other aspects.

Food additives: Diosmin can also be used as a food additive to improve the color, flavor and nutritional value of food. Due to its natural origin and biological activity, Diosmin is considered a safe and healthy food additive.